107-84-6

Purification Methods

Shake the chloride vigorously with 95% H2SO4 until the acid layer no longer becames coloured during 12hours, then wash it with water, saturated aqueous Na2CO3, and more water. Dry it with MgSO4, filter and fractionally distil it. Alternatively, a stream of oxygen containing 5% of ozone is passed through the chloride for a time, three times longer than is necessary to cause the first coloration of starch iodide paper by the exit gas. Subsequent washing of the liquid with aqueous NaHCO3 hydrolyses the ozonides and removes organic acids. After drying and filtering, the isoamyl chloride is distilled. [Chien & Willard J Am Chem Soc 75 6160 1953, Beilstein 1 IV 287.]

General Description

1-Chloro-3-methylbutane, also known as isopentyl chloride or isoamyl chloride, is a halogenated hydrocarbon with the molecular formula C5H11Cl. It is commonly used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and fragrances. 1-CHLORO-3-METHYLBUTANE is characterized by its reactivity in nucleophilic substitution reactions, where the chlorine atom can be displaced by various nucleophiles. It is a volatile, colorless liquid with a pungent odor, and its physical properties, such as boiling point and density, are consistent with those of typical alkyl chlorides. Safety precautions are necessary when handling due to its flammability and potential irritant effects.

Definition

Any of several compounds or mixtures thereof may be referred to by this name, since numerous isomers are possible, the most common of which is 1-chloro- 3-methylbutane. Combustible.