610-97-9
- Product Name：Methyl 2-iodobenzoate
- Molecular Formula：C8H7IO2
- Purity：99%
- Molecular Weight：262.047
Product Details
pd_meltingpoint:64 °C
Appearance:clear yellow liquid
Purity:99%
China cas 610-97-9 manufacturer wholesale Methyl 2-iodobenzoate at affordable price
- Molecular Formula:C8H7IO2
- Molecular Weight:262.047
- Appearance/Colour:clear yellow liquid
- Vapor Pressure:0.0134mmHg at 25°C
- Melting Point:64 °C
- Refractive Index:1.6052
- Boiling Point:258.8 °C at 760 mmHg
- Flash Point:110.3 °C
- PSA：26.30000
- Density:1.753 g/cm3
- LogP:2.07780
Methyl 2-iodobenzoate(Cas 610-97-9) Usage
|
Synthesis Reference(s) |
Journal of the American Chemical Society, 93, p. 4845, 1971 DOI: 10.1021/ja00748a030 |
|
General Description |
Methyl 2-iodobenzoate can be prepared from 2-iodobenzoic acid via esterification. It undergoes cobalt-catalyzed cyclization with aldehydes to form phthalide derivatives. The microbial dihydroxylation of methyl 2-iodobenzoate forms a nonracemic iodocyclohexene carboxylate intermediate. This intermediate forms the precursor for preparing kibdelone C. |
InChI:InChI=1/C8H7IO2/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5H,1H3
610-97-9 Relevant articles
Connecting binuclear Pd(III) and mononuclear Pd(IV) chemistry by Pd-Pd bond cleavage
Powers, David C.,Lee, Eunsung,Ariafard, Alireza,Sanford, Melanie S.,Yates, Brian F.,Canty, Allan J.,Ritter, Tobias
, p. 12002 - 12009 (2012)
Oxidation of binuclear Pd(II) complexes ...
Pd/Cu-Catalyzed Vinylation of Terminal Alkynes with (2-Bromoethyl)diphenylsulfonium Triflate
Ming, Xiao-Xia,Wu, Shuai,Tian, Ze-Yu,Song, Jia-Wei,Zhang, Cheng-Pan
supporting information, p. 6795 - 6800 (2021/09/08)
The potential of (2-bromoethyl)diphenyls...
Mechanochemical-Cascaded C-N Cross-Coupling and Halogenation Using N-Bromo- And N-Chlorosuccinimide as Bifunctional Reagents
Bera, Shyamal Kanti,Mal, Prasenjit
, p. 14144 - 14159 (2021/09/13)
Exploration of alternative energy source...
Method for preparing iodo-benzoic acid (ester) by improving moral Michael reaction
-
, (2021/11/03)
The invention discloses a method for pre...
Reconciling Electrostatic and n→π* Orbital Contributions in Carbonyl Interactions
Adam, Catherine,Borsley, Stefan,Cockroft, Scott L.,Ling, Kenneth B.,Mati, Ioulia K.,Muchowska, Kamila B.,Nichol, Gary S.,Pascoe, Dominic J.,Smolyar, Ivan V.
supporting information, p. 14602 - 14608 (2020/07/06)
Interactions between carbonyl groups are...
610-97-9 Process route
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-
67-56-1
methanol
-
-
88-67-5
2-Iodobenzoic acid
-
-
610-97-9
o-iodo-methyl-benzoic acid
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
Reflux;
|
100% |
|
With
sulfuric acid;
for 3h;
Reflux;
|
99% |
|
With
sulfuric acid;
at 80 ℃;
for 2.5h;
Inert atmosphere;
|
99% |
|
With
sulfuric acid;
Reflux;
Inert atmosphere;
|
98% |
|
With
sulfuric acid;
for 16h;
Reflux;
|
98% |
|
With
sulfuric acid;
at 65 ℃;
for 24h;
|
97% |
|
With
sulfuric acid;
at 0 - 20 ℃;
Reflux;
|
97% |
|
With
sulfuric acid;
Reflux;
|
97% |
|
With
sulfuric acid;
for 3h;
Reflux;
|
96% |
|
With
sulfuric acid;
for 2h;
Reflux;
|
96% |
|
With
sulfuric acid;
Heating;
|
95% |
|
With
sulfuric acid;
for 24h;
Reflux;
|
94% |
|
With
1,3,5-trichloro-2,4,6-triazine; sodium carbonate;
at 50 ℃;
for 0.333333h;
Sonication;
|
92% |
|
With
thionyl chloride;
at -10 - 20 ℃;
|
91% |
|
With
sulfuric acid;
for 3h;
Inert atmosphere;
Reflux;
|
91% |
|
With
thionyl chloride;
at 0 ℃;
for 4h;
Reflux;
|
90% |
|
With
sulfuric acid;
for 2.5h;
Heating;
|
89% |
|
With
sulfuric acid;
for 2.5h;
Inert atmosphere;
Reflux;
|
89% |
|
With
potassium carbonate;
In
acetonitrile;
at 50 ℃;
Reagent/catalyst;
Sealed tube;
Inert atmosphere;
Sonication;
|
89% |
|
With
sulfuric acid;
|
86% |
|
With
sulfuric acid;
Heating;
|
86% |
|
With
sulfuric acid;
at 0 - 90 ℃;
for 8h;
|
85% |
|
With
thionyl chloride;
for 3h;
Ambient temperature;
|
84% |
|
With
sulfuric acid;
for 2h;
Heating;
|
82% |
|
With
sulfuric acid;
for 3h;
Reflux;
Inert atmosphere;
|
75% |
|
With
Oxone;
In
toluene;
at 60 ℃;
for 48h;
Reagent/catalyst;
Time;
Green chemistry;
|
72% |
|
With
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione;
at 70 ℃;
for 20h;
|
58% |
|
With
N-Bromosuccinimide;
at 70 ℃;
for 20h;
|
55% |
|
With
chloro-trimethyl-silane;
In
tetrahydrofuran;
at 20 ℃;
for 36h;
|
49% |
|
With
hydrogenchloride;
for 30h;
Heating;
|
40% |
|
With
hydrogenchloride;
|
|
|
With
sulfuric acid;
|
|
|
With
hydrogen cation;
|
|
|
With
sulfuric acid;
|
|
|
With
sulfuric acid;
|
|
|
With
thionyl chloride;
at -10 - 20 ℃;
for 14.5h;
|
|
|
With
sulfuric acid;
for 3h;
Reflux;
|
|
|
With
sulfuric acid;
at 60 ℃;
Inert atmosphere;
|
|
|
With
sulfuric acid;
for 2h;
Inert atmosphere;
Reflux;
|
|
|
With
sulfuric acid;
for 24h;
Reflux;
|
|
|
methanol; 2-Iodobenzoic acid;
at 0 ℃;
for 0.166667h;
With
thionyl chloride;
for 6h;
Reflux;
|
|
|
With
sulfuric acid;
Reflux;
|
|
|
With
sulfuric acid;
In
water;
Reflux;
|
|
|
With
dmap; dicyclohexyl-carbodiimide;
In
dichloromethane;
at 23 - 25 ℃;
|
|
|
With
sulfuric acid;
at 80 ℃;
for 8h;
|
-
-
88-67-5
2-Iodobenzoic acid
-
-
610-97-9
o-iodo-methyl-benzoic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; methanol;
|
|
|
Multi-step reaction with 2 steps
1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / Inert atmosphere
2: oxalyl dichloride / dichloromethane / 0.5 h / Inert atmosphere
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
|
|
|
Multi-step reaction with 2 steps
1: thionyl chloride; N,N-dimethyl-formamide / benzene / 2 h / 80 °C
2: triethylamine / 2 h / 0 - 20 °C
With
thionyl chloride; triethylamine; N,N-dimethyl-formamide;
In
benzene;
|
|
|
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide; thionyl chloride / dichloromethane / 1 h
2: triethylamine / 0.5 h / 0 - 20 °C
With
thionyl chloride; triethylamine; N,N-dimethyl-formamide;
In
dichloromethane;
|
610-97-9 Upstream products
-
67-56-1
methanol
-
88-67-5
2-Iodobenzoic acid
-
105230-44-2
methyl 2-(tosyldiazenyl)benzoate
-
828-76-2
2-dichloroiodanyl-benzoic acid methyl ester
610-97-9 Downstream products
-
606-45-1
2-methoxybenzoic acid methyl ester
-
73183-74-1
2-(10-Phenothiazinyl)benzoesaeure-methylester
-
109747-49-1
2,2'-dicarboxyltriphenylamine
-
64511-19-9
6-(2-carboxy-phenyl)-benzo[1,3]dioxole-5-carboxylic acid
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-
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