589-87-7
- Product Name：1-Bromo-4-iodobenzene
- Molecular Formula：C6H4BrI
- Purity：99%
- Molecular Weight：282.906
Product Details
pd_meltingpoint:89-91 °C(lit.)
Appearance:white to brown cryst. powder, crystals or needles
Purity:99%
Quality Factory Supply 99% Pure 1-Bromo-4-iodobenzene 589-87-7 with Efficient Delivery
- Molecular Formula:C6H4BrI
- Molecular Weight:282.906
- Appearance/Colour:white to brown cryst. powder, crystals or needles
- Vapor Pressure:0.0464mmHg at 25°C
- Melting Point:89-91 °C(lit.)
- Refractive Index:1.654
- Boiling Point:244.8 °C at 760 mmHg
- Flash Point:101.9 °C
- PSA：0.00000
- Density:2.215 g/cm3
- LogP:3.05370
1-Bromo-4-iodobenzene(Cas 589-87-7) Usage
|
Synthesis methods |
Industrial parabromoaniline is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. The product processes structural characterization by IR and 1HNMR. The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene. Unit: Heilongjiang University of Chemistry and Materials Science Author: Guo Jing Bai Xuefeng Lvhong Fei |
|
General Description |
Vapour pressure as a function of temperature for 1-bromo-4-iodobenzene has been studied using a diaphragm manometer and torsion mass-loss effusion. |
InChI:InChI=1/C6H4BrI/c7-5-1-3-6(8)4-2-5/h1-4H
589-87-7 Relevant articles
Acidic ionic liquid supported on silica-coated magnetite nanoparticles as a green catalyst for one-pot diazotization-halogenation of the aromatic amines
Isaad, Jalal
, p. 49333 - 49341 (2014)
Acidic ionic liquid was immobilized on s...
The graphite-catalyzed: ipso -functionalization of arylboronic acids in an aqueous medium: metal-free access to phenols, anilines, nitroarenes, and haloarenes
Badgoti, Ranveer Singh,Dandia, Anshu,Parewa, Vijay,Rathore, Kuldeep S.,Saini, Pratibha,Sharma, Ruchi
, p. 18040 - 18049 (2021/05/29)
An efficient, metal-free, and sustainabl...
Hydrogen-Bond-Donor Solvents Enable Catalyst-Free (Radio)-Halogenation and Deuteration of Organoborons
Yang, Yi,Gao, Xinyan,Zeng, Xiaojun,Han, Junbin,Xu, Bo
supporting information, p. 1297 - 1300 (2020/12/23)
A hydrogen bond donor solvent assisted (...
Palladium-Catalyzed Decarbonylative Iodination of Aryl Carboxylic Acids Enabled by Ligand-Assisted Halide Exchange
Boehm, Philip,Cacherat, Bastien,Lee, Yong Ho,Martini, Tristano,Morandi, Bill
supporting information, p. 17211 - 17217 (2021/07/02)
We report an efficient and broadly appli...
Arene diazonium saccharin intermediates: A greener and cost-effective alternative method for the preparation of aryl iodide
Ghaffari Khaligh, Nader,Rafie Johan, Mohd,Shahnavaz, Zohreh,Zaharani, Lia
, p. 535 - 542 (2020/06/01)
In the current protocol, the arene diazo...
589-87-7 Process route
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-
201230-82-2
carbon monoxide
-
-
79054-62-9
1-bromo-4-iodoxybenzene
-
-
589-87-7
1,4-bromoiodobenzene
-
-
586-76-5
4-Bromobenzoic acid
-
-
100-21-0
terephthalic acid
| Conditions | Yield |
|---|---|
|
With
sodium tetrachloropalladate; sodium carbonate;
In
water;
at 40 ℃;
for 5h;
Yields of byproduct given;
|
15% 61% |
-
-
108-86-1,52753-63-6
bromobenzene
-
-
589-87-7
1,4-bromoiodobenzene
| Conditions | Yield |
|---|---|
|
With
trifluorormethanesulfonic acid; [bis(pyridine)iodine]+ tetrafluoroborate;
In
dichloromethane;
for 2h;
Ambient temperature;
|
90% |
|
With
sodium periodate; sulfuric acid; iodine;
In
acetic anhydride; acetic acid;
at 20 ℃;
for 5h;
|
87% |
|
With
cerium(III) chloride heptahydrate; dihydrogen peroxide; sodium iodide;
In
water;
for 12h;
regioselective reaction;
Reflux;
|
86% |
|
With
Oxone; sodium iodide;
In
water;
for 12h;
regioselective reaction;
Reflux;
|
85% |
|
With
N-iodo-succinimide; trifluoroacetic acid;
at 20 ℃;
for 3h;
regioselective reaction;
|
81% |
|
With
potassium bromate; hydrogenchloride; potassium iodide;
In
water; acetic acid;
at 80 ℃;
for 4h;
|
80% |
|
With
manganese(IV) oxide; sulfuric acid; iodine; acetic anhydride;
In
acetic acid;
1.) room temperature, 2 h, 2.) 45-55 deg C, 2 h, 3.) room temperature, overnight;
|
77% |
|
With
sodium dodecyl-sulfate; sodium iodide;
Ce(OH)3OOH;
at 20 ℃;
for 3h;
|
76% |
|
With
sulfuric acid; acetic anhydride; iodic acid;
In
acetic acid;
for 2h;
Heating;
|
71% |
|
With
chromium(VI) oxide; sulfuric acid; iodine;
In
acetic anhydride; acetic acid;
at 55 - 65 ℃;
for 1h;
|
68% |
|
With
sodium percarbonate; sulfuric acid; iodine;
acetic anhydride; acetic acid;
at 45 - 50 ℃;
for 2h;
|
68% |
|
With
sodium periodate; acetic anhydride; acetic acid;
sulfuric acid;
Heating;
|
66% |
|
With
dihydrogen peroxide; iodine; acetic anhydride; urea;
sulfuric acid;
In
acetic acid;
at 10 - 15 ℃;
|
65% |
|
With
iodine; bis-[(trifluoroacetoxy)iodo]benzene;
In
tetrachloromethane;
for 0.25h;
Ambient temperature;
|
63% |
|
With
iodine; bis-[(trifluoroacetoxy)iodo]benzene;
In
tetrachloromethane;
for 0.25h;
Ambient temperature;
|
63% |
|
With
sodium periodate; iodine; acetic acid;
sulfuric acid;
In
water;
at 90 ℃;
for 1.5h;
|
61% |
|
With
potassium permanganate; sulfuric acid; iodine;
In
acetic acid;
at 115 ℃;
for 2h;
|
58% |
|
With
manganese(IV) oxide; sulfuric acid; iodine;
In
acetic anhydride; acetic acid;
at 70 ℃;
for 1h;
|
53% |
|
With
dipotassium peroxodisulfate; choline chloride; iodine;
In
acetonitrile;
at 65 ℃;
for 5h;
|
51% |
|
With
sulfuric acid; Iodine monochloride;
at 90 - 95 ℃;
for 4h;
|
41% |
|
With
2,4,6,8-tetraiodo-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione;
In
sulfuric acid;
at 0 ℃;
for 0.25h;
|
40% |
|
With
potassium ferrate(VI); iodine;
In
hexane;
for 10h;
regioselective reaction;
Reflux;
|
40% |
|
With
iodine;
|
|
|
With
iodine; silver trifluoroacetate;
at 130 ℃;
|
|
|
With
iodine; nitric acid;
|
589-87-7 Upstream products
-
108-86-1
bromobenzene
-
591-50-4
iodobenzene
-
64-17-5
ethanol
-
17333-82-3
4-bromo-benzenediazonium ion
589-87-7 Downstream products
-
57102-42-8
N-(4-bromophenyl)carbazole
-
34328-32-0
4-Iod-4'-trifluormethylbenzophenon
-
25533-94-2
4-Brom-1-<6-H-perfluor-hexyl>-benzol
-
42834-34-4
4-[trans-2-(4-bromphenyl)vinyl]pyridine
Relevant Products
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Cyclopentyl bromideCAS：137-43-9
-
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-
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