5421-53-4
- Product Name：Bis(4-tert-butylphenyl)iodonium chloride
- Molecular Formula：C20H26I.Cl
- Purity：99%
- Molecular Weight：428.784
Product Details
pd_meltingpoint:213 °C
Purity:99%
High Quality Chinese Factory supply 5421-53-4 Bis(4-tert-butylphenyl)iodonium chloride
- Molecular Formula:C20H26I.Cl
- Molecular Weight:428.784
- Melting Point:213 °C
- PSA：0.00000
- LogP:-0.58600
NSC 8994(Cas 5421-53-4) Usage
|
General Description |
NSC 8994, also known as Clioquinol, is a halogenated 8-hydroxyquinoline derivative that has been used as an antiparasitic agent and topical disinfectant. It has also shown potential as a treatment for neurodegenerative diseases such as Alzheimer's and Parkinson's. However, its use has been limited due to concerns about its potential neurotoxicity and the development of subacute myelo-optic neuropathy, a severe and potentially irreversible side effect. It has also been investigated for its potential anti-cancer properties, with studies suggesting that it may inhibit the growth of certain tumor cells. Overall, NSC 8994 has demonstrated diverse pharmacological properties, but its use is limited by safety concerns and the need for further research. |
InChI:InChI=1/C20H26I/c1-19(2,3)15-7-11-17(12-8-15)21-18-13-9-16(10-14-18)20(4,5)6/h7-14H,1-6H3/q-1
5421-53-4 Relevant articles
Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts
Guérard, Fran?ois,Lee, Yong-Sok,Baidoo, Kwamena,Gestin, Jean-Fran?ois,Brechbiel, Martin W.
supporting information, p. 12332 - 12339 (2016/08/24)
Aryliodonium salts have become precursor...
Bottom Antireflective Coating Compositions
-
, (2009/05/29)
Developable bottom antireflective coatin...
BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS
-
Page/Page column 55-56, (2009/05/30)
Developable bottom antireflective coatin...
PHOTOACTIVE COMPOUNDS
-
Page/Page column 57, (2008/06/13)
The present application relates to a com...
5421-53-4 Process route
-
-
253185-03-4,253185-04-5
tert-butylbenzene
-
-
5421-53-4
4,4'-Di-tert-butyldiphenyliodonium chloride
| Conditions | Yield |
|---|---|
|
With
potassium iodate; sulfuric acid;
|
|
|
tert-butylbenzene;
With
potassium iodate; sulfuric acid; acetic anhydride;
In
dichloromethane;
at 5 - 10 ℃;
for 5h;
With
sodium chloride;
In
dichloromethane;
|
|
|
With
potassium iodate; sulfuric acid; sodium chloride;
In
hexane; dichloromethane; water;
|
|
|
tert-butylbenzene;
With
potassium iodate; sulfuric acid; acetic anhydride;
In
dichloromethane;
at 5 - 20 ℃;
With
sodium chloride;
In
dichloromethane; water;
|
-
-
142342-33-4
4,4'-di(tert-butyl)diphenyliodonium tosylate
-
-
5421-53-4
4,4'-Di-tert-butyldiphenyliodonium chloride
| Conditions | Yield |
|---|---|
|
With
potassium chloride;
In
water; acetonitrile;
at 60 ℃;
for 0.0833333h;
|
75% |
5421-53-4 Upstream products
-
253185-03-4
tert-butylbenzene
-
142342-33-4
4,4'-di(tert-butyl)diphenyliodonium tosylate
5421-53-4 Downstream products
-
68-12-2
N,N-dimethyl-formamide
-
88888-38-4
C21H28NO
-
64501-62-8
C18H20NO2
-
142342-33-4
4,4'-di(tert-butyl)diphenyliodonium tosylate
Relevant Products
-
Diphenyliodonium chlorideCAS：1483-72-3
-
1-Bromo-2-chloroethaneCAS：107-04-0
-
Methyl bromoacetateCAS：96-32-2
