5445-17-0
- Product Name：Methyl 2-bromopropionate
- Molecular Formula：C4H7BrO2
- Purity：99%
- Molecular Weight：167.002
Product Details
pd_meltingpoint:177-180 °C(Solv: water (7732-18-5))
Appearance:clear colourless to slightly yellow liquid
Purity:99%
Manufacturer Sells Best Quality Methyl 2-bromopropionate 5445-17-0 with stock
- Molecular Formula:C4H7BrO2
- Molecular Weight:167.002
- Appearance/Colour:clear colourless to slightly yellow liquid
- Vapor Pressure:4.76mmHg at 25°C
- Melting Point:177-180 °C(Solv: water (7732-18-5))
- Refractive Index:n20/D 1.451(lit.)
- Boiling Point:145.9 °C at 760 mmHg
- Flash Point:47.1 °C
- PSA：26.30000
- Density:1.496 g/cm3
- LogP:0.94280
Methyl 2-bromopropionate(Cas 5445-17-0) Usage
InChI:InChI=1/C4H7BrO2/c1-3(5)4(6)7-2/h3H,1-2H3/t3-/m1/s1
5445-17-0 Relevant articles
Engineering Orthogonal Methyltransferases to Create Alternative Bioalkylation Pathways
Bennett, Matthew R.,Cronin, Victoria A.,Herbert, Abigail J.,Micklefield, Jason,Shepherd, Sarah A.,Sung, Rehana
supporting information, p. 14950 - 14956 (2020/07/04)
S-adenosyl-l-methionine (SAM)-dependent ...
Iron-catalysed enantioselective Suzuki-Miyaura coupling of racemic alkyl bromides
Iwamoto, Takahiro,Okuzono, Chiemi,Adak, Laksmikanta,Jin, Masayoshi,Nakamura, Masaharu
supporting information, p. 1128 - 1131 (2019/01/28)
The first iron-catalysed enantioselectiv...
Synthesis of [13C3]-B6 vitamers labelled at three consecutive positions starting from [13C3]-propionic acid
Bachmann, Thomas,Rychlik, Michael
, (2018/09/11)
[13C3]-labelled vitamers (PN, PL and PM)...
Cobalt-bisoxazoline-catalyzed asymmetric kumada cross-coupling of racemic α-bromo esters with aryl grignard reagents
Mao, Jianyou,Liu, Feipeng,Wang, Min,Wu, Lin,Zheng, Bing,Liu, Shangzhong,Zhong, Jiangchun,Bian, Qinghua,Walsh, Patrick J.
supporting information, p. 17662 - 17668 (2015/02/02)
The first cobalt-catalyzed asymmetric Ku...
5445-17-0 Process route
-
-
5445-17-0
Methyl 2-bromopropionate
-
-
27871-49-4,2155-30-8
(S)-Methyl lactate
-
-
20047-41-0,57885-43-5,5445-17-0,62076-23-7
methyl (2S)-2-bromopropanoate
| Conditions | Yield |
|---|---|
|
With
Rhodococcus rhodochrous haloalkane dehalogenase;
at 21 ℃;
pH=8.2;
optical yield given as %ee;
enantioselective reaction;
Tris sulfate buffer;
Resolution of racemate;
Enzymatic reaction;
|
-
-
67-56-1
methanol
-
-
598-72-1,10327-08-9
2-Bromopropionic acid
-
-
5445-17-0
Methyl 2-bromopropionate
| Conditions | Yield |
|---|---|
|
With
dmap; dicyclohexyl-carbodiimide;
In
diethyl ether;
at 25 ℃;
for 3h;
Inert atmosphere;
|
65% |
|
With
thionyl chloride;
at 0 - 20 ℃;
for 12h;
|
48% |
|
With
sulfuric acid;
|
|
|
With
benzene;
|
|
|
With
hydrogen cation;
Heating;
|
|
|
With
toluene-4-sulfonic acid;
In
toluene;
for 2h;
Reflux;
|
5445-17-0 Upstream products
-
67-56-1
methanol
-
563-76-8
α-bromopropionyl bromide
-
598-72-1
2-Bromopropionic acid
-
79-03-8
propionyl chloride
5445-17-0 Downstream products
-
119020-91-6
methyl 3,3-diphenyl-3-hydroxy-2-methyl-propanoate
-
940-31-8
2-phenoxypropionic acid
-
17639-76-8
methyl 2-methoxypropionate
-
2065-24-9
methyl 2-phenoxypropanoate
Relevant Products
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4-Bromobenzoic acidCAS：586-76-5
-
9-AnthraldehydeCAS：642-31-9
-
N,N,N',N'-Tetrakis(4-methylphenyl)-benzidineCAS：76185-65-4
